Yoshio Goshima Selected Research

Phenylephrine (Neo-Synephrine)

7/2014	Impaired nitric oxide production and increased blood pressure in systemic heterozygous ATP2B1 null mice.
4/2012	Mice lacking hypertension candidate gene ATP2B1 in vascular smooth muscle cells show significant blood pressure elevation.

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Yoshio Goshima Research Topics

Disease

12	Parkinson Disease (Parkinson's Disease) 01/2023 - 06/2002
8	Ocular Albinism 01/2023 - 01/2014
6	Schizophrenia (Dementia Praecox) 03/2024 - 09/2015
6	Neoplasms (Cancer) 02/2022 - 11/2011
5	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 02/2005
5	Spinal Cord Injuries (Spinal Cord Injury) 07/2021 - 12/2006
4	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 11/2011
3	Autistic Disorder (Autism) 03/2024 - 09/2015
3	Neoplasm Metastasis (Metastasis) 07/2016 - 11/2011
3	Inflammation (Inflammations) 03/2016 - 01/2013
2	Low Tension Glaucoma 04/2024 - 08/2022
2	Optic Nerve Injuries 10/2019 - 01/2019
2	Nervous System Diseases (Neurological Disorders) 01/2018 - 01/2017
2	Cicatrix (Scar) 03/2016 - 02/2015
2	Wounds and Injuries (Trauma) 03/2016 - 01/2016
2	Hypersensitivity (Allergy) 01/2015 - 01/2011
2	Vascular Ring 07/2014 - 04/2012
2	Pruritus (Itching) 09/2012 - 12/2008
1	Cognitive Dysfunction 03/2024
1	Epilepsy (Aura) 03/2024
1	Parkinsonian Disorders (Parkinsonism) 01/2024
1	Catalepsy 01/2024
1	Mental Disorders (Mental Disorder) 01/2024
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 07/2023
1	Pulmonary Hypertension 02/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022
1	Tobacco Use Disorder (Nicotine Dependence) 10/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2020
1	Memory Disorders (Memory Loss) 12/2019
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2019
1	Pheochromocytoma 09/2019
1	Wallerian Degeneration 01/2019
1	Hemorrhage 01/2018
1	Obesity 09/2017
1	Pancreatitis 07/2016
1	Chronic Pancreatitis 07/2016
1	Neurodevelopmental Disorders 05/2016
1	Diabetes Mellitus 01/2016
1	Sepsis (Septicemia) 09/2015
1	Disease Progression 02/2015
1	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 01/2015
1	Breast Neoplasms (Breast Cancer) 11/2014
1	Lung Neoplasms (Lung Cancer) 11/2014

Drug/Important Bio-Agent (IBA)

21	Semaphorin-3AIBA 04/2024 - 06/2006
18	Proteins (Proteins, Gene)FDA Link 04/2024 - 03/2008
8	Levodopa (L Dopa)FDA LinkGeneric 01/2024 - 01/2014
7	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 06/2002
6	Dihydroxyphenylalanine (Dopa)IBA 03/2015 - 06/2002
4	Amino Acids FDA Link 01/2023 - 06/2002
3	levodopa receptorIBA 01/2024 - 10/2020
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2011
3	Aromatic-L-Amino-Acid DecarboxylasesIBA 09/2016 - 06/2002
3	Messenger RNA (mRNA)IBA 11/2014 - 09/2012
2	Methamphetamine (Desoxyn)FDA LinkGeneric 07/2023 - 10/2016
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023 - 11/2014
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2020 - 01/2016
2	Nerve Growth Factor (NGF)IBA 09/2019 - 09/2012
2	LithiumIBA 01/2018 - 01/2017
2	Retinaldehyde (Retinal)IBA 11/2014 - 07/2009
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 07/2014 - 04/2012
2	Semaphorins (Semaphorin)IBA 09/2012 - 11/2011
2	Triglycerides (Triacylglycerol)IBA 07/2012 - 07/2012
2	EnzymesIBA 02/2003 - 06/2002
1	Lactic Acid (Lactate)FDA LinkGeneric 03/2024
1	Antipsychotic Agents (Antipsychotics)IBA 01/2024
1	Cholinergic Agents (Cholinergics)IBA 01/2024
1	Haloperidol (Haldol)FDA LinkGeneric 01/2024
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2024
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2024
1	Methylphenidate (Ritalin)FDA LinkGeneric 07/2023
1	Therapeutic UsesIBA 01/2023
1	collapsin response mediator protein-2IBA 08/2022
1	MonocrotalineIBA 02/2022
1	Nicotine FDA Link 10/2020
1	lanthionine ketimineIBA 01/2020
1	EstersIBA 01/2020
1	ProteomeIBA 12/2019
1	Amyloid beta-PeptidesIBA 12/2019
1	Serine (L-Serine)FDA Link 10/2019
1	Glycogen Synthase KinasesIBA 01/2019
1	maleic acid (maleate)IBA 01/2018
1	Neprilysin (Neutral Endopeptidase)IBA 09/2017
1	Fibrillin-1IBA 09/2017
1	ElastinIBA 09/2017
1	Nogo ReceptorsIBA 01/2017
1	CeruletideIBA 07/2016
1	Nerve Growth Factors (Neurotrophins)IBA 03/2016
1	Neuroprotective AgentsIBA 03/2016
1	Chondroitin Sulfate ProteoglycansIBA 01/2016
1	Tyrosine (L-Tyrosine)FDA Link 01/2016
1	Phosphates (Orthophosphate)IBA 01/2016
1	LipopolysaccharidesIBA 09/2015
1	Monoclonal AntibodiesIBA 09/2015
1	AntibodiesIBA 09/2015
1	Phenylalanine (L-Phenylalanine)FDA Link 03/2015
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2015
1	Ophthalmic Solutions (Eye Drops)IBA 01/2015

Therapy/Procedure

3	Therapeutics 01/2019 - 09/2002
1	Subcutaneous Injections 02/2022
1	Ayurvedic Medicine (Siddha Medicine) 01/2016